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When zolpidem was administered at oral doses of 4, 20, and 100 mg base/kg (approximat and 100 times the MRHD on a mg/m 2 basis) to pregnant rats during the period of organogenesis, dose-related decreases in fetal skull ossification occurred at all but the lowest dose, which is approximately 4 times the MRHD on a mg/m 2 basis. theophylline anhydrous reviews Ambien Interactions. There are 472 drugs known to interact with Ambien (zolpidem), along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 29 are major, 440 are moderate, and 3 are minor. Ambien (zolpidem) is a sedative used to treat insomnia, which helps 20 mg, while zolpidem tartrate 10 mg was difficult to distinguish from placebo.
